User:Eric Martz/Sandbox 5

The collaborative, 3D encyclopedia of proteins and other molecules.

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Here's an excerpt from one of our pages (1eve):

The anti-Alzheimer's drug E2020 (marketed as Aricept&reg;) is an inhibitor that binds acetylcholinesterase (AChE) with high affinity. The X-ray structure of the E2020-AChE (AChE from Torpedo california) complex shows that E2020 has a unique orientation  along the active-site gorge, extending from the anionic subsite (W84 ) of the active site, at the bottom, to the peripheral anionic site (near W279 ), at the top, via aromatic stacking interactions with conserved aromatic acid residues. E2020 does not, however, interact directly with either the catalytic triad or the 'oxyanion hole' but only indirectly via solvent molecules .

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Search Proteopedia using the search box in the toolbar to the left. See also Help:Searching. Proteopedia already contains >50,000 pages, including an automatically-generated page for every published macromolecular 3D structure (to see some of these, click Random Page in the navigation box at the upper left), plus Topic Pages providing an overview of a class of molecules or other structural topics.

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 * The Proteopedia Video Guide is a narrated video guide that serves both as a starting point as well as a reference.
 * The Editing Help Page.
 * The help page for the Scene authoring tools.
 * Proteopedia:Policies

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You may protect your teaching pages from unwanted editing by others -- see Help:Protected Pages. You may protect such pages from unwanted editing by others -- see Help:Protected Pages.
 * Scientists and Students: a reference resource for understanding protein 3D structure-function relationships. Example: Acetylcholinesterase bound to Aricept, an anti-Alzheimer's drug.
 * Educators: develop tutorials or molecular scenes to project during lectures, or for student use. Examples: Teaching Scenes, Tutorials, and Educators' Pages. Assign students to construct pages in Proteopedia for class projects or reports: see Student Projects. See also Teaching Strategies Using Proteopedia.
 * Structural Researchers: create supplementary materials for your journal publications, and pages about your research team or institute, highlighting structures you have researched. For examples, see Research Groups.

Proteopedia Mission Statement
To collect, organize and disseminate structural and functional knowledge about protein, RNA, DNA, and other macromolecules, and their assemblies and interactions with small molecules, in a manner that is relevant and broadly accessible to students and scientists.

Goals for Proteopedia

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 * To continue to develop the concept of tying text to three-dimensional, interactive images.
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 * To foster collaborations between students and experts, signed with their real names.

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